Precision Medicine Ends 13-Year Infertility Struggle at Birla Fertility & IVF Gorakhpur

Gorakhpur : For Asha and Manish (names changed), the dream of parenthood felt like a distant memory after thirteen years of clinical disappointment. Having endured five failed fertility treatments—including three IVF cycles and multiple donor attempts at various centers—the couple arrived at Birla Fertility & IVF, Gorakhpur, exhausted but seeking one last answer.

Under the expertise of Dr. Akriti Gupta, Centre Head & Consultant, the clinical team moved away from the "more is better" approach. The challenge was multifaceted: Asha had a severely low ovarian reserve (AMH 0.16) and a history of complex surgeries, while Manish faced suboptimal sperm parameters.

Rather than repeating standard protocols, Dr. Gupta focused on "Precision and Sequencing." The breakthrough came through a series of deliberate, high-tech interventions:

Microfluidics: Used for superior sperm selection to ensure the highest quality embryos.

Genetic Testing (PGT-A): Both embryos were tested and confirmed as "euploid" (genetically healthy) before transfer.

ERA (Endometrial Receptivity Analysis): This was the turning point. The test revealed that Asha’s "window of implantation" was shifted to 108 hours, rather than the standard 102 hours.

By timing the embryo transfer precisely to Asha’s unique biological window, the team achieved a positive pregnancy in the very first attempt at the center.

"Success often lies in precision, not intensity," said Dr. Akriti Gupta. "Once we addressed the uterine environment and identified the shifted implantation window, the path became clear."

This case highlights a shift in reproductive medicine: success is found when clinical expertise aligns perfectly with a patient's unique genetic and biological timeline. After over a decade of searching, the couple finally found their success through science-backed, compassionate care.