Eye Test May Soon Detect TB, Says Dr. Parvez Khan's Research

Kanpur: A groundbreaking study by Dr. Parvez Khan, Head of the Department of Ophthalmology at GSVM Medical College, suggests that a simple eye examination could soon be used to detect Tuberculosis (TB). This discovery could revolutionize TB diagnosis, allowing for earlier treatment and potentially saving millions from this debilitating disease.

TB remains a major health concern in India, often made more severe by co-existing conditions like diabetes and AIDS. A significant challenge in treating TB is the severe side effects of its medications. One such potent anti-TB drug, Ethambutol, is particularly harmful to the eyes. Long-term use of this drug can deplete copper and zinc from the optic nerves, damaging the mitochondria and often leading to irreversible vision loss. Until now, a reliable treatment for this side effect has been elusive.

Driven by this problem, Dr. Khan dedicated four years to researching a solution. His study involved administering a combination of cilostazol, pentoxifylline, and Vitamin B-12 to patients suffering from Ethambutol-induced vision loss. The results were remarkable: patients showed significant improvement in their vision, which was further confirmed by a Visual Evoked Potential (VEP) test.

This pivotal research has been published in an international journal of the European Society of Medicine, bringing global recognition to Dr. Khan's work. The positive outcomes have also earned him an invitation to present his findings at the prestigious Delhi Retina Forum conference, a testament to the study's significance.

Dr. Khan credits the success of his research to the guidance and encouragement provided by Dr. Sanjay Kala, the Principal of GSVM Medical College. He emphasized that such innovative research thrives in an environment that actively supports and promotes academic inquiry.

This development is particularly crucial for countries like India, where TB is prevalent. The ability to detect TB through an eye test could facilitate early diagnosis, especially in hard-to-reach populations. Moreover, the discovery of a treatment for Ethambutol's side effects offers a glimmer of hope to countless patients who fear losing their sight while undergoing TB treatment. Dr. Khan's research is a major step forward in making TB treatment safer and more effective.